Absent babies in a crowded world

Absent babies in a crowded world

Women in Germany can have it all, it seems. They can have seven children, as many pets, a Mr Right, and a brilliant career crowned with a government appointment. Well, at least one woman can, namely the Federal minister for family and youth, Ursula von der Leyen. Since she was appointed last November, von der Leyen has been showing off her own biography as an example for all. Only slowly, if ev...

Abandoned babies and absent policies.

OBJECT Although infant abandonment is a historical problem, we know remarkably little about the conditions or effects of abandonment to guide evidence driven policies. This paper briefly reviews the existing international evidence base with reference to potential mental health considerations before mapping current UK guidelines and procedures, and available incidence data. Limitations arising f...

Calcineurin in a Crowded World

Calcineurin is a Ser/Thr phosphatase that is important for key biological processes, including immune system activation. We previously identified a region in the intrinsically disordered regulatory domain of calcineurin that forms a critical amphipathic α-helix (the "distal helix") that is required for complete activation of calcineurin. This distal helix was shown to have a Tm close to that of...

Life in a crowded world.

Introduction Macromolecules are present as soluble species and/or structural arrays at total concentrations of up to several hundred grams per litre in essentially all physiological compartments. Although local composition varies widely between different systems, it is evident that most macromolecular reactions and processes in vivo—as opposed to typical experiments in vitro in which the total ...

A Brave New World of Designer Babies